I am a current MSc Bioinformatics student at the University of Bristol with a strong background in microbial genomics research. My passion lies in leveraging computational tools to tackle critical human health challenges. I am eager to apply and learn cutting-edge bioinformatics skills to contribute to innovative solutions and collaborate with a team at the forefront of the field.
Contributed to data-driven microbial informatics research by analyzing whole-genome sequencing data of over 5,000 WHO priority pathogens.
Contributed to development of bioinformatics pipelines to streamline the extraction of valuable insights from raw sequencing data from Illumina and Nanopore platforms.
Effectively communicated research findings through presentations at two international and one national conference and periodic journal club presentations.
Aseptic techniques, microbial culture, and identification of patient samples from various sources using both conventional and automated methods.
Hands-on experience with advanced microbiology lab equipment for performing identification (ID) and antimicrobial susceptibility testing (AST) using VITEK®-2. Proficiently analyzed and interpreted results for research purposes and patient report generation.
Skills Summary
Computational Skills Python, R, Shell, Nextflow, Docker, Git, Linux, Anaconda, Miniconda, HPC and Slurm, Open-Source Tools and Technologies Open-Source Platforms Bioconda, Bioconductor, CRAN, nf-core, BioPython Genome Assembly and QC SPAdes, Velvet, Flye, QUAST, BUSCO, Trimmomatic, FASTQC, LIGHTER, MASH, Seqtk, MultiQC Sequence Alignment MUSCLE, Clustal Omega, MAFFT SNP Analysis BWA, GATK, SAMtools, bedtools, Snippy, SNP-sites, FreeBayes, Picard, VCFtools, BCFtools Phylogeny Roary, Panaroo, Ggtree, Bactdating, BEAST, IQ-TREE, Gubbins, FastTree, iTOL, Microreact Data Mining and Retrieval NCBI, European Nucleotide Archive (ENA), NCBI Variation Viewer, Ensembl, UCSC (Genome Browser, Table Browser), Galaxy, IGV, dbSNP, ClinVar, SNPEffect and SNPedia AMR Analysis and Annotation AMRFinderPlus, ABRICATE, ResFinder, Prokka, Bakta, Kleborate, CRISPR-CAS FINDER, Bactinspector Molecular docking and Drug Discovery Autodock vina, Biovia Discovery studio, iGEMDock, SwissADME Lab Techniques Basics of Sequencing using Illumina and Oxford Nanopore platforms, DNA/RNA extraction, Qubit, Nanodrop, Gel Electrophoresis, ID & AST using VITEK, Microbiology Aseptic Techniques Soft skills Collaborative Working, Problem-Solving, Adaptability, Time Management, Attention to Detail, Scientific Writing, Critical Thinking, Research Ethics
Masters — Bioinformatics, University of Bristol, Bristol, United Kingdom. Bachelors — Biotechnology Engineering, Dayananda Sagar College of Engineering, Bangalore, India. 2019 - 2023
Data Manipulation Proficiency: Gained expertise in reading, writing, indexing, selecting, and assigning data within Pandas DataFrames.
Summary Functions and Maps: Learned to effectively extract insights from data using summary functions and apply custom transformations with mapping functions.
Data Cleaning and Handling: Acquired proficiency in handling missing values, renaming columns, and combining data from different sources.
Integration with Other Bioinformatics Tools: Learned how to integrate Pandas with other bioinformatics tools and libraries for a comprehensive analysis workflow.
Drug Discovery offered by UC SanDiego on Coursera Aug 2023 Key Takeaways
Comprehensive understanding of the drug discovery pipeline: Gained insights into the various stages of drug development, from target identification to clinical trials.
Proficiency in genomics and proteomics: Developed basic skills in analyzing and interpreting genomic and proteomic data for drug target identification and efficacy assessment.
Data-driven decision-making: Understood the importance of data-driven approaches in drug discovery and how bioinformatics can inform decision-making throughout the process.
Marketing and Pricing: Learn how to develop effective marketing strategies and pricing models based on market needs and clinical data.
Strategic Alliance and Portfolio Management: Understand the importance of forming strategic partnerships and managing a diverse drug portfolio for successful market launch.
Regulatory Considerations: Gain knowledge of the regulatory landscape surrounding drug approval and post-marketing surveillance.
Industry Expertise: Benefit from the perspectives of faculty and industry experts, providing a comprehensive understanding of the commercialization process.
Industrial Biotechnology offered by University of Manchester on Coursera July 2022 Key Takeaways
Strong understanding of fundamental biological concepts: The course provided a solid foundation in biotechnology, including principles of biochemistry, molecular biology, and microbiology.
Understanding of sustainable manufacturing: Recognized the role of industrial biotechnology in developing sustainable and environmentally friendly manufacturing processes.
Knowledge of bioinformatics tools and techniques: Gained familiarity with essential bioinformatics tools and techniques used in industrial biotechnology applications.
Conferences
13th meeting of the International Society of Pneumonia and Pneumococcal Diseases (ISPPD) Cape Town, South Africa- Poster presentation on “Unraveling Capsular Switching in Indian Streptococcus pneumoniae isolates: Insights from a Comprehensive Genomic Analysis”
The 3rd International Symposium on Streptococcus agalactiae Disease (ISSAD), Rio de Janeiro - Poster presentation on “Insights into pbp Allelic mutations conferring resistance to Beta-Lactams in GBS isolates from India”
National Conference on Recent Trends in Biosciences and Healthcare, SRM Institute of Technology, Chennai, India - Oral Presentation on “Genetic diversity and in silico resistance prediction of ST147 Klebsiella pneumoniae Indian isolates”
National Level Project Competition hosted by MSRIT, Bangalore, India - Poster presentation on “Green synthesis of MgO Nanoparticles from Annona muricata plant as a therapeutic aid”
3-Day National Conference on Biotechnology for Better Life hosted by Sir MVIT, Bangalore, India - Poster presentation on “Phytochemical Screening and Assessment of Antibacterial activity using Methanolic leaf extract of Annona muricata plant”